Operational complexity versus design efficiency: challenges of implementing a phase IIa multiple parallel cohort targeted treatment platform trial in advanced breast cancer

BACKGROUND: Platform trial designs are used increasingly in cancer clinical research and are considered an efficient model for evaluating multiple compounds within a single disease or disease subtype. However, these trial designs can be challenging to operationalise. The use of platform trials in on...

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Detalles Bibliográficos
Autores principales: Snowdon, Claire, Kernaghan, Sarah, Moretti, Laura, Turner, Nicholas C., Ring, Alistair, Wilkinson, Katie, Martin, Sue, Foster, Stephanie, Kilburn, Lucy S., Bliss, Judith M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077636/
https://www.ncbi.nlm.nih.gov/pubmed/35526005
http://dx.doi.org/10.1186/s13063-022-06312-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077636/
https://www.ncbi.nlm.nih.gov/pubmed/35526005
http://dx.doi.org/10.1186/s13063-022-06312-x

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