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Activation of complement C1q and C3 in glomeruli might accelerate the progression of diabetic nephropathy: Evidence from transcriptomic data and renal histopathology

AIMS/INTRODUCTION: It is not unclear whether the complement system is involved in the pathogenesis of diabetic nephropathy (DN). We explored the role of the complement system in glomeruli from patients with DN using integrated transcriptomic bioinformatics analysis and renal histopathology. MATERIAL...

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Detalles Bibliográficos
Autores principales: Jiao, Yuanyuan, Jiang, Shimin, Wang, Ying, Yu, Tianyu, Zou, Guming, Zhuo, Li, Li, Wenge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077730/
https://www.ncbi.nlm.nih.gov/pubmed/34932275
http://dx.doi.org/10.1111/jdi.13739