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Pitch-tunable pillar arrays for high-throughput culture and immunohistological analysis of tumor spheroids
Tumor spheroids are multicellular, three-dimensional (3D) cell culture models closely mimicking the microenvironments of human tumors in vivo, thereby providing enhanced predictability, clinical relevancy of drug efficacy and the mechanism of action. Conventional confocal microscopic imaging remains...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077751/ https://www.ncbi.nlm.nih.gov/pubmed/35539534 http://dx.doi.org/10.1039/c7ra09090k |