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A novel tRNA-derived fragment AS-tDR-007333 promotes the malignancy of NSCLC via the HSPB1/MED29 and ELK4/MED29 axes

BACKGROUND: Transfer RNA-derived fragments (tRFs) are a new class of small non-coding RNAs. Recent studies suggest that tRFs participate in some pathological processes. However, the biological functions and mechanisms of tRFs in non-small cell lung cancer (NSCLC) are largely unknown. METHODS: Differ...

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Detalles Bibliográficos
Autores principales: Yang, Wenhan, Gao, Kaiping, Qian, Youhui, Huang, Yongyi, Xiang, Qin, Chen, Cheng, Chen, Qianqian, Wang, Yiling, Fang, Fuyuan, He, Qihan, Chen, Siqi, Xiong, Juan, Chen, Yangchao, Xie, Ni, Zheng, Duo, Zhai, Rihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077895/
https://www.ncbi.nlm.nih.gov/pubmed/35526007
http://dx.doi.org/10.1186/s13045-022-01270-y