Off-targetP ML: an open source machine learning framework for off-target panel safety assessment of small molecules

Unpredicted drug safety issues constitute the majority of failures in the pharmaceutical industry according to several studies. Some of these preclinical safety issues could be attributed to the non-selective binding of compounds to targets other than their intended therapeutic target, causing undes...

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Detalles Bibliográficos
Autores principales: Naga, Doha, Muster, Wolfgang, Musvasva, Eunice, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077900/
https://www.ncbi.nlm.nih.gov/pubmed/35525988
http://dx.doi.org/10.1186/s13321-022-00603-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077900/
https://www.ncbi.nlm.nih.gov/pubmed/35525988
http://dx.doi.org/10.1186/s13321-022-00603-w

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