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A novel role of lysophosphatidic acid (LPA) in human myeloma resistance to proteasome inhibitors

Lysophosphatidic acid (LPA) is a naturally occurring phospholipid that regulates cell proliferation, survival, and migration. However, its role on human multiple myeloma (MM) cells is largely unknown. In this study, we show that LPA, which is highly elevated in MM patients, plays an important role i...

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Detalles Bibliográficos
Autores principales: Su, Pan, Xiao, Liuling, Ye, Lingqun, Wang, Zhuo, Xiong, Wei, Wang, Qiang, Ma, Xingzhe, Xian, Miao, Yang, Maojie, Zu, Youli, Pingali, Sai Ravi, Qian, Jianfei, Yi, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9077919/
https://www.ncbi.nlm.nih.gov/pubmed/35526043
http://dx.doi.org/10.1186/s13045-022-01269-5