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Probing the stereoselectivity of OleD-catalyzed glycosylation of cardiotonic steroids

The glycosyltransferase OleD variant as a catalyst for the glycosylation of four pairs of epimers of cardiotonic steroids (CTS) are assessed. The results of this study demonstrated that the OleD-catalyze glycosylation of CTS is significantly influenced by the configuration at C-3 and the A/B fusion...

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Detalles Bibliográficos
Autores principales: Zhu, Xue-Lin, Wen, Chao, Ye, Qing-Mei, Xu, Wei, Zou, Deng-Lang, Liang, Guang-Ping, Zhang, Fan, Chen, Wan-Na, Jiang, Ren-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078122/
https://www.ncbi.nlm.nih.gov/pubmed/35542447
http://dx.doi.org/10.1039/c7ra11979h