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Probing the stereoselectivity of OleD-catalyzed glycosylation of cardiotonic steroids
The glycosyltransferase OleD variant as a catalyst for the glycosylation of four pairs of epimers of cardiotonic steroids (CTS) are assessed. The results of this study demonstrated that the OleD-catalyze glycosylation of CTS is significantly influenced by the configuration at C-3 and the A/B fusion...
Autores principales: | Zhu, Xue-Lin, Wen, Chao, Ye, Qing-Mei, Xu, Wei, Zou, Deng-Lang, Liang, Guang-Ping, Zhang, Fan, Chen, Wan-Na, Jiang, Ren-Wang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078122/ https://www.ncbi.nlm.nih.gov/pubmed/35542447 http://dx.doi.org/10.1039/c7ra11979h |
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