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Green synthesis of new pyrrolidine-fused spirooxindoles via three-component domino reaction in EtOH/H(2)O

An efficient, green and sustainable approach for the synthesis of novel polycyclic pyrrolidine-fused spirooxindole compounds was developed. The synthesis included a one-pot, three-component, domino reaction of (E)-3-(2-nitrovinyl)-indoles, isatins and chiral polycyclic α-amino acids under catalyst-f...

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Detalles Bibliográficos
Autores principales: Wang, Yong-Chao, Wang, Jun-Liang, Burgess, Kevin S., Zhang, Jiang-Wei, Zheng, Qiu-Mei, Pu, Ya-Dan, Yan, Li-Jun, Chen, Xue-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078157/
https://www.ncbi.nlm.nih.gov/pubmed/35539589
http://dx.doi.org/10.1039/c7ra13207g