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Affinity requirements for control of synaptic targeting and neuronal cell survival by heterophilic IgSF cell adhesion molecules

Neurons in the developing brain express many different cell adhesion molecules (CAMs) on their surfaces. CAM-binding affinities can vary by more than 200-fold, but the significance of these variations is unknown. Interactions between the immunoglobulin superfamily CAM DIP-α and its binding partners,...

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Detalles Bibliográficos
Autores principales: Xu, Shuwa, Sergeeva, Alina P., Katsamba, Phinikoula S., Mannepalli, Seetha, Bahna, Fabiana, Bimela, Jude, Zipursky, S. Lawrence, Shapiro, Lawrence, Honig, Barry, Zinn, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078203/
https://www.ncbi.nlm.nih.gov/pubmed/35385751
http://dx.doi.org/10.1016/j.celrep.2022.110618