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Surface-grafted polyethylene glycol conformation impacts the transport of PEG-functionalized liposomes through a tumour extracellular matrix model

The effect of surface PEGylation on nanoparticle transport through an extracellular matrix (ECM) is an important determinant for tumor targeting success. Fluorescent stealth liposomes (base lipid DOPC) were prepared incorporating different proportions of PEG-grafted lipids (2.5, 5 and 10% of the tot...

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Detalles Bibliográficos
Autores principales: Labouta, Hagar I., Gomez-Garcia, M. Juliana, Sarsons, Christopher D., Nguyen, Trinh, Kennard, Jacob, Ngo, Wayne, Terefe, Kaisha, Iragorri, Nicolas, Lai, Patrick, Rinker, Kristina D., Cramb, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078461/
https://www.ncbi.nlm.nih.gov/pubmed/35539117
http://dx.doi.org/10.1039/c7ra13438j