N-Acetyl-l-leucine-polyethylenimine-mediated miR-34a delivery improves osteogenesis and bone formation in vitro and in vivo

Oral bone defects are difficult to treat. Recently, endogenous miR-34a was shown to be involved in bone anabolism. Clinical application of such microRNAs requires the inherent instability of microRNAs to be overcome by an efficient delivery system. In this study, we employed N-acetyl-l-leucine-modif...

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Detalles Bibliográficos
Autores principales: Shen, Yuqin, Liu, Yin, Gao, Han, Fei, Hongbo, Yu, Wenwen, Hu, Tianqi, Zheng, Yi, Bi, Xueting, Lin, Chongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078501/
https://www.ncbi.nlm.nih.gov/pubmed/35542025
http://dx.doi.org/10.1039/c7ra12548h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078501/
https://www.ncbi.nlm.nih.gov/pubmed/35542025
http://dx.doi.org/10.1039/c7ra12548h

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