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The development and application of in silico models for drug induced liver injury

Drug-induced liver injury (DILI), caused by drugs, herbal agents or nutritional supplements, is a major issue for patients and the pharmaceutical industry. It has been a leading cause of clinical trials failure and withdrawal of FDA approval. In this research, we focused on in silico estimation of c...

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Detalles Bibliográficos
Autores principales: Li, Xiao, Chen, Yaojie, Song, Xinrui, Zhang, Yuan, Li, Huanhuan, Zhao, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078522/
https://www.ncbi.nlm.nih.gov/pubmed/35542036
http://dx.doi.org/10.1039/c7ra12957b