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The development and application of in silico models for drug induced liver injury
Drug-induced liver injury (DILI), caused by drugs, herbal agents or nutritional supplements, is a major issue for patients and the pharmaceutical industry. It has been a leading cause of clinical trials failure and withdrawal of FDA approval. In this research, we focused on in silico estimation of c...
Autores principales: | Li, Xiao, Chen, Yaojie, Song, Xinrui, Zhang, Yuan, Li, Huanhuan, Zhao, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078522/ https://www.ncbi.nlm.nih.gov/pubmed/35542036 http://dx.doi.org/10.1039/c7ra12957b |
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