An in vitro affinity-based method for studying herb–drug interactions for direct identification of cytochrome P450 1A2, 3A4, and 2C9 specific ligands from herbal extracts using ultrafiltration-high performance liquid chromatography

A novel in vitro strategy for affinity-based ultrafiltration-high performance liquid chromatography (HPLC) was developed for the direct identification of cytochrome P450 (CYP) 1A2, 3A4, and 2C9 specific ligands from Danshen extracts, in which human liver microsome (HLM) was used as the source of CYP...

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Detalles Bibliográficos
Autores principales: Wang, Zhiqiang, Hwang, Seung Hwan, Zuo, Guanglei, Kim, Set Byeol, Lim, Soon Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078662/
https://www.ncbi.nlm.nih.gov/pubmed/35539875
http://dx.doi.org/10.1039/c7ra12161j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078662/
https://www.ncbi.nlm.nih.gov/pubmed/35539875
http://dx.doi.org/10.1039/c7ra12161j

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