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An efficient and scalable synthesis of potent TLR2 agonistic PAM(2)CSK(4)
Diacylated PAM(2)CSK(4), a highly expensive lipopeptide with desirable aqueous solubility and a broad spectrum of cytokine/chemokine induction is a most potent dual (human and murine) Toll-Like Receptor-2 (TLR2) agonist. Besides such thrilling characteristics, its synthetic process is not reported i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078680/ https://www.ncbi.nlm.nih.gov/pubmed/35540846 http://dx.doi.org/10.1039/c8ra01387j |