Insights into the mechanism of concomitant nucleation of form II and ethanol solvate of spironolactone in cooling crystallization

The concomitant crystallization of spironolactone form II and its ethanol solvate was investigated in ethanol by means of process analytical techniques, such as particle vision and measurement (PVM), focused beam reflectance measurement (FBRM) and Raman spectroscopy. The concomitant crystals were ch...

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Detalles Bibliográficos
Autores principales: Jia, Lihong, Yin, Qiuxiang, Zhou, Lina, Zhang, Xia, Wang, Chang, Du, Wei, Zhou, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078732/
https://www.ncbi.nlm.nih.gov/pubmed/35540856
http://dx.doi.org/10.1039/c7ra13094e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078732/
https://www.ncbi.nlm.nih.gov/pubmed/35540856
http://dx.doi.org/10.1039/c7ra13094e

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