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Insights into the mechanism of concomitant nucleation of form II and ethanol solvate of spironolactone in cooling crystallization
The concomitant crystallization of spironolactone form II and its ethanol solvate was investigated in ethanol by means of process analytical techniques, such as particle vision and measurement (PVM), focused beam reflectance measurement (FBRM) and Raman spectroscopy. The concomitant crystals were ch...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078732/ https://www.ncbi.nlm.nih.gov/pubmed/35540856 http://dx.doi.org/10.1039/c7ra13094e |