Preparation, in vitro and in vivo evaluation, and molecular dynamics (MD) simulation studies of novel F-18 labeled tumor imaging agents targeting focal adhesion kinase (FAK)

Focal adhesion kinase (FAK) has been identified as a promising target in the early diagnosis and therapy of tumor. In this work, we obtained and evaluated another two novel pyrimidine-based F-18 labeled tumor imaging agents targeting FAK. Among them, the corresponding F-19 standards [(19)F]2, displa...

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Detalles Bibliográficos
Autores principales: Fang, Yu, Wang, Dawei, Xu, Xingyu, Dava, Gila, Liu, Jianping, Li, Xiang, Xue, Qianqian, Wang, Huan, Zhang, Jiangshan, Zhang, Huabei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078890/
https://www.ncbi.nlm.nih.gov/pubmed/35540451
http://dx.doi.org/10.1039/c8ra00652k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078890/
https://www.ncbi.nlm.nih.gov/pubmed/35540451
http://dx.doi.org/10.1039/c8ra00652k

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