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Preparation, in vitro and in vivo evaluation, and molecular dynamics (MD) simulation studies of novel F-18 labeled tumor imaging agents targeting focal adhesion kinase (FAK)
Focal adhesion kinase (FAK) has been identified as a promising target in the early diagnosis and therapy of tumor. In this work, we obtained and evaluated another two novel pyrimidine-based F-18 labeled tumor imaging agents targeting FAK. Among them, the corresponding F-19 standards [(19)F]2, displa...
Autores principales: | Fang, Yu, Wang, Dawei, Xu, Xingyu, Dava, Gila, Liu, Jianping, Li, Xiang, Xue, Qianqian, Wang, Huan, Zhang, Jiangshan, Zhang, Huabei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9078890/ https://www.ncbi.nlm.nih.gov/pubmed/35540451 http://dx.doi.org/10.1039/c8ra00652k |
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