Allele-specific aberration of imprinted domain chromosome architecture associates with large offspring syndrome

Large offspring syndrome (LOS) and Beckwith-Wiedemann syndrome are similar epigenetic congenital overgrowth conditions in ruminants and humans, respectively. We have reported global loss-of-imprinting, methylome epimutations, and gene misregulation in LOS. However, less than 4% of gene misregulation...

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Detalles Bibliográficos
Autores principales: Li, Yahan, Boadu, Frimpong, Highsmith, Max R., Hagen, Darren E., Cheng, Jianlin, Rivera, Rocío Melissa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079005/
https://www.ncbi.nlm.nih.gov/pubmed/35542046
http://dx.doi.org/10.1016/j.isci.2022.104269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079005/
https://www.ncbi.nlm.nih.gov/pubmed/35542046
http://dx.doi.org/10.1016/j.isci.2022.104269

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