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Circular RNA circVAMP3 promotes aerobic glycolysis and proliferation by regulating LDHA in renal cell carcinoma

Metabolic dysfunction is seen in cancer cells where increased glycolysis provides energy for growth. Circular RNAs (circRNAs) are thought to assist in glucose metabolism and the switch to glycolysis. Through screening, we found that circVAMP3 was necessary for both glycolytic and proliferative activ...

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Detalles Bibliográficos
Autores principales: Li, Jun, Zhang, Qian, Guan, Yupeng, Liao, Dingzhun, Jiang, Donggen, Xiong, Haiyun, Zhan, Hengji, Pang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079058/
https://www.ncbi.nlm.nih.gov/pubmed/35525866
http://dx.doi.org/10.1038/s41419-022-04863-0