FBXO2 targets glycosylated SUN2 for ubiquitination and degradation to promote ovarian cancer development

SAD1/UNC84 domain protein-2 (SUN2) plays a tumor suppressor role in various types of cancer by inhibiting cancer cell proliferation, migration and promoting apoptosis. However, the post-translational regulation of SUN2 and the cellular mechanism responsible for its proteasomal degradation remains la...

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Detalles Bibliográficos
Autores principales: Ji, Jing, Shen, Jing, Xu, Yuxin, Xie, Mengru, Qian, Qilan, Qiu, Teng, Shi, Wen, Ren, Dexu, Ma, Jinming, Liu, Wei, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079088/
https://www.ncbi.nlm.nih.gov/pubmed/35525855
http://dx.doi.org/10.1038/s41419-022-04892-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079088/
https://www.ncbi.nlm.nih.gov/pubmed/35525855
http://dx.doi.org/10.1038/s41419-022-04892-9

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