Oxime derivative TFOBO promotes cell death by modulating reactive oxygen species and regulating NADPH oxidase activity in myeloid leukemia

Several derivatives derived from the oxime structure have been reported as potential anticancer agents in various cancers. Here, we first tested a novel oxime-containing derivative of 2-((2,4,5-trifluorobenzyl)oxy)benzaldehyde oxime (TFOBO) to evaluate its anticancer effect in myeloid leukemic cells...

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Detalles Bibliográficos
Autores principales: Jo, Ahyoung, Kwak, Jae-Hwan, Woo, Soo-Yeon, Kim, Bo-Young, Son, Yonghae, Choi, Hee-Seon, Kim, Jayoung, Kwon, Munju, Cho, Hyok-Rae, Eo, Seong-Kug, Nam, Ji Ho, Kim, Hyung-Sik, Baryawno, Ninib, Lee, Dongjun, Kim, Koanhoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079095/
https://www.ncbi.nlm.nih.gov/pubmed/35525902
http://dx.doi.org/10.1038/s41598-022-11543-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079095/
https://www.ncbi.nlm.nih.gov/pubmed/35525902
http://dx.doi.org/10.1038/s41598-022-11543-8

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