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Oxime derivative TFOBO promotes cell death by modulating reactive oxygen species and regulating NADPH oxidase activity in myeloid leukemia
Several derivatives derived from the oxime structure have been reported as potential anticancer agents in various cancers. Here, we first tested a novel oxime-containing derivative of 2-((2,4,5-trifluorobenzyl)oxy)benzaldehyde oxime (TFOBO) to evaluate its anticancer effect in myeloid leukemic cells...
Autores principales: | Jo, Ahyoung, Kwak, Jae-Hwan, Woo, Soo-Yeon, Kim, Bo-Young, Son, Yonghae, Choi, Hee-Seon, Kim, Jayoung, Kwon, Munju, Cho, Hyok-Rae, Eo, Seong-Kug, Nam, Ji Ho, Kim, Hyung-Sik, Baryawno, Ninib, Lee, Dongjun, Kim, Koanhoi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079095/ https://www.ncbi.nlm.nih.gov/pubmed/35525902 http://dx.doi.org/10.1038/s41598-022-11543-8 |
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