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Conformational ensemble of the TNF-derived peptide solnatide in solution

Tumor necrosis factor (TNF) is a homotrimer that has two spatially distinct binding regions, three lectin-like domains (LLD) at the TIP of the protein and three basolaterally located receptor-binding sites, the latter of which are responsible for the inflammatory and cell death-inducing properties o...

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Detalles Bibliográficos
Autores principales: Martin-Malpartida, Pau, Arrastia-Casado, Silvia, Farrera-Sinfreu, Josep, Lucas, Rudolf, Fischer, Hendrik, Fischer, Bernhard, Eaton, Douglas C., Tzotzos, Susan, Macias, Maria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079168/
https://www.ncbi.nlm.nih.gov/pubmed/35601958
http://dx.doi.org/10.1016/j.csbj.2022.04.031