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Dapsone is an anticatalysis for Alzheimer’s disease exacerbation

Brain inflammation generally accelerates neurodegeneration. Alzheimer’s disease (AD) triggers an innate immune response by activating a cytosolic DNA sensor cyclic-GMP-AMP synthase (cGAS)/stimulator of interferon genes (STING) signaling pathway. Our study investigated patients with leprosy and AD. T...

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Detalles Bibliográficos
Autores principales: Lee, Jong Hoon, Kanwar, Badar, Lee, Chul Joong, Sergi, Consolato, Coleman, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079171/
https://www.ncbi.nlm.nih.gov/pubmed/35542045
http://dx.doi.org/10.1016/j.isci.2022.104274