BAG6 prevents the aggregation of neurodegeneration-associated fragments of TDP43

Neurodegeneration is associated with the aggregation of proteins bearing solvent-exposed hydrophobicity as a result of their misfolding and/or proteolytic cleavage. An understanding of the cellular protein quality control mechanisms which prevent protein aggregation is fundamental to understanding t...

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Detalles Bibliográficos
Autores principales: Kasu, Yasar Arfat T., Arva, Akshaya, Johnson, Jess, Sajan, Christin, Manzano, Jasmin, Hennes, Andrew, Haynes, Jacy, Brower, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079172/
https://www.ncbi.nlm.nih.gov/pubmed/35542047
http://dx.doi.org/10.1016/j.isci.2022.104273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079172/
https://www.ncbi.nlm.nih.gov/pubmed/35542047
http://dx.doi.org/10.1016/j.isci.2022.104273

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