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Functionalization of α-hydroxyphosphonates as a convenient route to N-tosyl-α-aminophosphonates

Direct conversion of the α-hydroxyl group by para-toluenesulfonamide to yield α-(N-tosyl)aminophosphonates is reported. α-Aminophosphonates 23a,b–37a,b were obtained from the corresponding α-hydroxyphosphonates 6a,b–21a,b in the presence of K(2)CO(3), via the retro-Abramov reaction of the appropriat...

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Detalles Bibliográficos
Autores principales: Cytlak, Tomasz, Skibińska, Monika, Kaczmarek, Patrycja, Kaźmierczak, Marcin, Rapp, Magdalena, Kubicki, Maciej, Koroniak, Henryk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079259/
https://www.ncbi.nlm.nih.gov/pubmed/35539392
http://dx.doi.org/10.1039/c8ra01656a