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Delivery of modified mRNA encoding vesicular stomatitis virus matrix protein for colon cancer gene therapy
Plasmid DNA based gene delivery has been widely utilized among both pre-clinical and clinical gene therapy studies. However, therapeutic efficiency is usually limited by the size and potential immune-stimulation issue of plasmid backbone. As an alternative form of genetic material, chemically modifi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079296/ https://www.ncbi.nlm.nih.gov/pubmed/35539419 http://dx.doi.org/10.1039/c7ra13656k |