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Delivery of modified mRNA encoding vesicular stomatitis virus matrix protein for colon cancer gene therapy

Plasmid DNA based gene delivery has been widely utilized among both pre-clinical and clinical gene therapy studies. However, therapeutic efficiency is usually limited by the size and potential immune-stimulation issue of plasmid backbone. As an alternative form of genetic material, chemically modifi...

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Detalles Bibliográficos
Autores principales: Men, Ke, Zhang, Rui, Zhang, Xueyan, Huang, Rong, Zhu, Guonian, Tong, Rongsheng, Yang, Li, Wei, Yuquan, Duan, Xingmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079296/
https://www.ncbi.nlm.nih.gov/pubmed/35539419
http://dx.doi.org/10.1039/c7ra13656k