Chemical activation of prolyl hydroxylase-2 by BBAP-1 down regulates hypoxia inducible factor-1α and fatty acid synthase for mammary gland chemoprevention

(4-[7-(Acetyloxy)-2-ethyl-2H-chromen-3-yl] phenyl acetate) (BBAP-1) was identified as a potential prolyl hydroxylase-2 activator and tested for this activity using the 2-oxoglutarate dependent in vitro assay. BBAP-1 was evaluated for its cytotoxic potential against ER + MCF-7 cells, and N-methyl-N-n...

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Detalles Bibliográficos
Autores principales: Singh, Manjari, Devi, Uma, Roy, Subhadeep, Gupta, Pushpraj S., Kaithwas, Gaurav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079607/
https://www.ncbi.nlm.nih.gov/pubmed/35541235
http://dx.doi.org/10.1039/c8ra01239c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079607/
https://www.ncbi.nlm.nih.gov/pubmed/35541235
http://dx.doi.org/10.1039/c8ra01239c

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