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Evaluating Ylehd, a recombinant epoxide hydrolase from Yarrowia lipolytica as a potential biocatalyst for the resolution of benzyl glycidyl ether

Glycidyl ethers and their vicinal diols are important building blocks in the organic synthesis of anti-cancer and anti-obesity drugs. Ylehd, an epoxide hydrolase from tropical marine yeast Yarrowia lipolytica, was explored for its enantioselective properties by kinetic, thermodynamic and in silico s...

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Detalles Bibliográficos
Autores principales: Bendigiri, Chandrika, Harini, K., Yenkar, Sajal, Zinjarde, Smita, Sowdhamini, R., RaviKumar, Ameeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079618/
https://www.ncbi.nlm.nih.gov/pubmed/35541265
http://dx.doi.org/10.1039/c8ra00628h