MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) transplantation is a promising therapy for Alzheimer's disease (AD). However, hUC-MSCs cultured in vitro easily exhibit replicative senescence, which restricts their application. Although MG53 protein demonstrates multiple roles for...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Shanshan, Zhou, Xinkui, Wang, Yaping, Li, Zhe, Wang, Yingying, Shi, Jijing, Guan, Fangxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079718/
https://www.ncbi.nlm.nih.gov/pubmed/35525026
http://dx.doi.org/10.1016/j.redox.2022.102325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079718/
https://www.ncbi.nlm.nih.gov/pubmed/35525026
http://dx.doi.org/10.1016/j.redox.2022.102325

Ejemplares similares