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MG53 protein rejuvenates hUC-MSCs and facilitates their therapeutic effects in AD mice by activating Nrf2 signaling pathway

Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) transplantation is a promising therapy for Alzheimer's disease (AD). However, hUC-MSCs cultured in vitro easily exhibit replicative senescence, which restricts their application. Although MG53 protein demonstrates multiple roles for...

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Detalles Bibliográficos
Autores principales:	Ma, Shanshan, Zhou, Xinkui, Wang, Yaping, Li, Zhe, Wang, Yingying, Shi, Jijing, Guan, Fangxia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079718/ https://www.ncbi.nlm.nih.gov/pubmed/35525026 http://dx.doi.org/10.1016/j.redox.2022.102325

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