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A novel treatment strategy of HER2-targeted therapy in combination with Everolimus for HR+/HER2- advanced breast cancer patients with HER2 mutations

The incidence of HER2 somatic mutations in breast cancer is about 2–4%, mainly occurring in the HR+/HER2- subtype. Preclinical studies suggest that HER2 mutations can lead to constitutive HER2 activation, but effective treatment options for the clinical management of patients with HER2 mutations rem...

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Detalles Bibliográficos
Autores principales: Ma, Jing, Li, Xuelu, Zhang, Qianran, Li, Ning, Sun, Siwen, Zhao, Shanshan, Zhao, Zuowei, Li, Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079719/
https://www.ncbi.nlm.nih.gov/pubmed/35523006
http://dx.doi.org/10.1016/j.tranon.2022.101444