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Conservation of the conformational dynamics and ligand binding within M49 enzyme family

The hydrogen deuterium exchange (HDX) mass spectrometry combined with molecular dynamics (MD) simulations was employed to investigate conformational dynamics and ligand binding within the M49 family (dipeptidyl peptidase III family). Six dipeptidyl peptidase III (DPP III) orthologues, human, yeast,...

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Detalles Bibliográficos
Autores principales: Kazazić, Saša, Karačić, Zrinka, Sabljić, Igor, Agić, Dejan, Tomin, Marko, Abramić, Marija, Dadlez, Michal, Tomić, Antonija, Tomić, Sanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079729/
https://www.ncbi.nlm.nih.gov/pubmed/35542530
http://dx.doi.org/10.1039/c7ra13059g