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Conservation of the conformational dynamics and ligand binding within M49 enzyme family
The hydrogen deuterium exchange (HDX) mass spectrometry combined with molecular dynamics (MD) simulations was employed to investigate conformational dynamics and ligand binding within the M49 family (dipeptidyl peptidase III family). Six dipeptidyl peptidase III (DPP III) orthologues, human, yeast,...
Autores principales: | Kazazić, Saša, Karačić, Zrinka, Sabljić, Igor, Agić, Dejan, Tomin, Marko, Abramić, Marija, Dadlez, Michal, Tomić, Antonija, Tomić, Sanja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079729/ https://www.ncbi.nlm.nih.gov/pubmed/35542530 http://dx.doi.org/10.1039/c7ra13059g |
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