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Preparation and physicochemical characterization of camptothecin conjugated poly amino ester–methyl ether poly ethylene glycol copolymer

In the present study, camptothecin grafted poly amino ester-methyl ether polyethylene glycol (CPT-PEA-MPEG) as a novel copolymer was synthesized by Michael reaction at different ratios of MPEG and CPT (60 : 40 and 80 : 20). The microemulsion was used to prepare nanomicelles, and in vitro cytotoxicit...

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Detalles Bibliográficos
Autores principales: Fattahi, Ali, Karimi, Nadia, Rahmati, Fatemeh, Shokoohinia, Yalda, Sadrjavadi, Komail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079732/
https://www.ncbi.nlm.nih.gov/pubmed/35541238
http://dx.doi.org/10.1039/c8ra01407h