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A short and efficient total synthesis of the bromotyrosine-derived alkaloid psammaplysene A

Psammaplysene A, an inhibitor of FOXO1a-mediated nuclear export, has been synthesized by a concise and improved route from tyrosine-derived acid and amine fragments which were easily constructed using commercially available p-hydroxybenzaldehyde and tyramine as starting material, respectively. The s...

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Detalles Bibliográficos
Autores principales: Xu, Jingjing, Wang, Kai, Wu, Jinlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079787/
https://www.ncbi.nlm.nih.gov/pubmed/35539328
http://dx.doi.org/10.1039/c8ra02052c