Nicotinamide Mononucleotide Alleviates Cardiomyopathy Phenotypes Caused by Short-Chain Enoyl-Coa Hydratase 1 Deficiency

Short-chain enoyl-CoA hydratase 1 (ECHS1) deficiency plays a role in cardiomyopathy. Whether ECHS1 deficiency causes or is only associated with cardiomyopathy remains unclear. By using Echs1 heterogeneous knockout (Echs1(+/-)) mice, we found that ECHS1 deficiency caused cardiac dysfunction, as evide...

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Detalles Bibliográficos
Autores principales: Cai, Ke, Wang, Feng, Lu, Jia-Quan, Shen, An-Na, Zhao, Shi-Min, Zang, Wei-Dong, Gui, Yong-Hao, Zhao, Jian-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079797/
https://www.ncbi.nlm.nih.gov/pubmed/35540099
http://dx.doi.org/10.1016/j.jacbts.2021.12.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079797/
https://www.ncbi.nlm.nih.gov/pubmed/35540099
http://dx.doi.org/10.1016/j.jacbts.2021.12.007

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