Towards controlling the crystallisation behaviour of fenofibrate melt: triggers of crystallisation and polymorphic transformation

Fenofibrate (FEN) is a dyslipidemia treatment agent which is poorly soluble in water. FEN has tendency to form polymorphs and its crystallisation behaviour is difficult to predict. The nucleation process can be initiated by mechanical disruption such as ball milling or surface scratching which may r...

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Detalles Bibliográficos
Autores principales: Tipduangta, Pratchaya, Takieddin, Khaled, Fábián, László, Belton, Peter, Qi, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079832/
https://www.ncbi.nlm.nih.gov/pubmed/35542519
http://dx.doi.org/10.1039/c8ra01182f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079832/
https://www.ncbi.nlm.nih.gov/pubmed/35542519
http://dx.doi.org/10.1039/c8ra01182f

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