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Towards controlling the crystallisation behaviour of fenofibrate melt: triggers of crystallisation and polymorphic transformation
Fenofibrate (FEN) is a dyslipidemia treatment agent which is poorly soluble in water. FEN has tendency to form polymorphs and its crystallisation behaviour is difficult to predict. The nucleation process can be initiated by mechanical disruption such as ball milling or surface scratching which may r...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079832/ https://www.ncbi.nlm.nih.gov/pubmed/35542519 http://dx.doi.org/10.1039/c8ra01182f |