Celastrol delays hepatic steatosis and carcinogenesis in a rapid AKT/c-Met-transfected hepatocellular carcinoma model via suppressing fatty acid synthase expression and AKT/ERK phosphorylation

Although the suppressing effects of celastrol on hepatocellular carcinoma (HCC) have been demonstrated, evidence for the targeting of fatty acid synthetase (FASN) in the development of HCC by celastrol is still rare. In this study, the effect of celastrol on a rapid HCC model featuring co-activation...

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Detalles Bibliográficos
Autores principales: Hu, Junjie, Li, Xin, Zhou, Junxuan, Zhang, Cong, Zheng, Guohua, Qiu, Zhenpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079895/
https://www.ncbi.nlm.nih.gov/pubmed/35539339
http://dx.doi.org/10.1039/c8ra00522b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079895/
https://www.ncbi.nlm.nih.gov/pubmed/35539339
http://dx.doi.org/10.1039/c8ra00522b

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