Room-temperature borylation and one-pot two-step borylation/Suzuki–Miyaura cross-coupling reaction of aryl chlorides

A highly efficient room-temperature borylation strategy of aryl chlorides is described. Utilizing Buchwald's second-generation preformed catalyst, boronate esters were obtained for a wide range of substrates in high yield. The method was also applied to Suzuki–Miyaura cross-coupling reaction in...

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Detalles Bibliográficos
Autores principales: Ji, Hong, Wu, Li-Yang, Cai, Jiang-Hong, Li, Guo-Rong, Gan, Na-Na, Wang, Zhao-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079898/
https://www.ncbi.nlm.nih.gov/pubmed/35539348
http://dx.doi.org/10.1039/c8ra01381k
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author Ji, Hong
Wu, Li-Yang
Cai, Jiang-Hong
Li, Guo-Rong
Gan, Na-Na
Wang, Zhao-Hua
author_facet Ji, Hong
Wu, Li-Yang
Cai, Jiang-Hong
Li, Guo-Rong
Gan, Na-Na
Wang, Zhao-Hua
author_sort Ji, Hong
collection PubMed
description A highly efficient room-temperature borylation strategy of aryl chlorides is described. Utilizing Buchwald's second-generation preformed catalyst, boronate esters were obtained for a wide range of substrates in high yield. The method was also applied to Suzuki–Miyaura cross-coupling reaction in a one-pot two-step sequential manner, providing a facile and convenient access to the direct synthesis of biaryl compounds from aryl chlorides.
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spelling pubmed-90798982022-05-09 Room-temperature borylation and one-pot two-step borylation/Suzuki–Miyaura cross-coupling reaction of aryl chlorides Ji, Hong Wu, Li-Yang Cai, Jiang-Hong Li, Guo-Rong Gan, Na-Na Wang, Zhao-Hua RSC Adv Chemistry A highly efficient room-temperature borylation strategy of aryl chlorides is described. Utilizing Buchwald's second-generation preformed catalyst, boronate esters were obtained for a wide range of substrates in high yield. The method was also applied to Suzuki–Miyaura cross-coupling reaction in a one-pot two-step sequential manner, providing a facile and convenient access to the direct synthesis of biaryl compounds from aryl chlorides. The Royal Society of Chemistry 2018-04-11 /pmc/articles/PMC9079898/ /pubmed/35539348 http://dx.doi.org/10.1039/c8ra01381k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Ji, Hong
Wu, Li-Yang
Cai, Jiang-Hong
Li, Guo-Rong
Gan, Na-Na
Wang, Zhao-Hua
Room-temperature borylation and one-pot two-step borylation/Suzuki–Miyaura cross-coupling reaction of aryl chlorides
title Room-temperature borylation and one-pot two-step borylation/Suzuki–Miyaura cross-coupling reaction of aryl chlorides
title_full Room-temperature borylation and one-pot two-step borylation/Suzuki–Miyaura cross-coupling reaction of aryl chlorides
title_fullStr Room-temperature borylation and one-pot two-step borylation/Suzuki–Miyaura cross-coupling reaction of aryl chlorides
title_full_unstemmed Room-temperature borylation and one-pot two-step borylation/Suzuki–Miyaura cross-coupling reaction of aryl chlorides
title_short Room-temperature borylation and one-pot two-step borylation/Suzuki–Miyaura cross-coupling reaction of aryl chlorides
title_sort room-temperature borylation and one-pot two-step borylation/suzuki–miyaura cross-coupling reaction of aryl chlorides
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079898/
https://www.ncbi.nlm.nih.gov/pubmed/35539348
http://dx.doi.org/10.1039/c8ra01381k
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