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Towards potent but less toxic nanopharmaceuticals – lipoic acid bioconjugates of ultrasmall gold nanoparticles with an anticancer drug and addressing unit

Modification of ultrasmall gold nanoparticles (AuNPs) with the lipoic acid derivative of folic acid was found to enhance their accumulation in the cancer cell, as compared to AuNPs without addressing units. The application of lipoic acid enabled the control of the gold nanoparticle functionalities l...

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Detalles Bibliográficos
Autores principales: Dzwonek, Maciej, Załubiniak, Dominika, Piątek, Piotr, Cichowicz, Grzegorz, Męczynska-Wielgosz, Sylwia, Stępkowski, Tomasz, Kruszewski, Marcin, Więckowska, Agnieszka, Bilewicz, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079921/
https://www.ncbi.nlm.nih.gov/pubmed/35541347
http://dx.doi.org/10.1039/c8ra01107a