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Yunnanterpene G, a spiro-triterpene from the roots of Cimicifuga foetida, downregulates the expression of CD147 and MMPs in PMA differentiated THP-1 cells

A new cycloartane triterpene, yunnanterpene G (1), containing an oxaspiro[5.4]decane moiety, was purified from the roots of Cimicifuga foetida. The new structure was determined from spectroscopic data and the X-ray diffraction method. Biological evaluations revealed that compound 1 significantly inh...

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Detalles Bibliográficos
Autores principales: Lu, Ni-Hong, Zhang, Zi-Wei, Guo, Rui-Wei, Yang, Li-Xia, Song, Ya-Xian, Ye, Jin-Shan, Shi, Yan-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079972/
https://www.ncbi.nlm.nih.gov/pubmed/35541353
http://dx.doi.org/10.1039/c8ra01895b