Cargando…

Yunnanterpene G, a spiro-triterpene from the roots of Cimicifuga foetida, downregulates the expression of CD147 and MMPs in PMA differentiated THP-1 cells

A new cycloartane triterpene, yunnanterpene G (1), containing an oxaspiro[5.4]decane moiety, was purified from the roots of Cimicifuga foetida. The new structure was determined from spectroscopic data and the X-ray diffraction method. Biological evaluations revealed that compound 1 significantly inh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Ni-Hong, Zhang, Zi-Wei, Guo, Rui-Wei, Yang, Li-Xia, Song, Ya-Xian, Ye, Jin-Shan, Shi, Yan-Kun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2018
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9079972/ https://www.ncbi.nlm.nih.gov/pubmed/35541353 http://dx.doi.org/10.1039/c8ra01895b

Ejemplares similares

Trinor-cycloartane Glycosides from the Rhizomes of Cimicifuga foetida
por: Lu, Lu, et al.
Publicado: (2009)

Cycloartane Glycosides from the Roots of Cimicifuga foetida with Wnt Signaling Pathway Inhibitory Activity
por: Zhu, Di-Fan, et al.
Publicado: (2015)

Cytotoxic Cycloartane Triterpenoid Saponins from the Rhizomes of Cimicifuga foetida
por: Lu, Jing, et al.
Publicado: (2019)

Antiacetylcholinesterase triterpenes from the fruits of Cimicifuga yunnanensis
por: Nian, Yin, et al.
Publicado: (2018)

Six New 9,19-Cycloartane Triterpenoids from Cimicifuga foetida L.
por: Zhu, Guo-Lei, et al.
Publicado: (2016)

New triterpenes from Cimicifuga yunnanensis down-regulating the mRNA expression of CD147, MMP-2, and MMP-9
por: Lu, Ni-Hong, et al.
Publicado: (2021)

New Triterpene Diglycosides from the Rhizome of Cimifuga foetida
por: Sun, Lirong, et al.
Publicado: (2008)

Investigation of Antioxidant Interactions between Radix Astragali and Cimicifuga foetida and Identification of Synergistic Antioxidant Compounds
por: Wang, Fei, et al.
Publicado: (2014)

Involvement of CD147 in overexpression of MMP-2 and MMP-9 and enhancement of invasive potential of PMA-differentiated THP-1
por: Zhou, Jun, et al.
Publicado: (2005)

Ultrasonographic Observation of the Breast in Early Postmenopausal Women during Therapy with Cimicifuga Foetida Extract and Sequential Therapy with Estrogen and Progestin
por: Gaowa, Sharen, et al.
Publicado: (2015)

Fibrous Roots of Cimicifuga Are at Risk of Hepatotoxicity
por: Yu, Yang, et al.
Publicado: (2022)

Cimicifoetisides A and B, two cytotoxic cycloartane triterpenoid glycosides from the rhizomes of Cimicifuga foetida, inhibit proliferation of cancer cells
por: Sun, Li-Rong, et al.
Publicado: (2007)

The in Vitro and in Vivo Antitumor Activities of Tetracyclic Triterpenoids Compounds Actein and 26-Deoxyactein Isolated from Rhizome of Cimicifuga foetida L.
por: Wu, Desong, et al.
Publicado: (2016)

Optimization of differentiation and transcriptomic profile of THP-1 cells into macrophage by PMA
por: Liu, Tiezhu, et al.
Publicado: (2023)

Two New Triterpene Glycosides with Monomethyl Malonate Groups from the Rhizome of Cimifuga foetida L.
por: Sun, Li-Rong, et al.
Publicado: (2011)

KHF16 is a Leading Structure from Cimicifuga foetida that Suppresses Breast Cancer Partially by Inhibiting the NF-κB Signaling Pathway
por: Kong, Yanjie, et al.
Publicado: (2016)

Cimicifuga, Corrigendum
por: Guernsey, Wm. Jefferson
Publicado: (1887)

Cimicifuga Racemosa
por: Simpson,, et al.
Publicado: (1861)

New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment
por: Yue, Grace Gar-Lee, et al.
Publicado: (2016)

PMA-Induced THP-1 Macrophage Differentiation is Not Impaired by Citrate-Coated Platinum Nanoparticles
por: Gatto, Francesca, et al.
Publicado: (2017)

Effect of Melittin on Metabolomic Profile and Cytokine Production in PMA-Differentiated THP-1 Cells
por: Alqarni, Abdulmalik M., et al.
Publicado: (2018)

Metabolomic Profiling of the Immune Stimulatory Effect of Eicosenoids on PMA-Differentiated THP-1 Cells
por: Alqarni, Abdulmalik M., et al.
Publicado: (2019)

Secondary Metabolites with Anti-Inflammatory from the Roots of Cimicifuga taiwanensis
por: Chen, Jih-Jung, et al.
Publicado: (2022)

The Identification of Markers of Macrophage Differentiation in PMA-Stimulated THP-1 Cells and Monocyte-Derived Macrophages
por: Daigneault, Marc, et al.
Publicado: (2010)

Differential susceptibility to lipopolysaccharide affects the activation of toll-like-receptor 4 signaling in THP-1 cells and PMA-differentiated THP-1 cells
por: Kim, Young Kyu, et al.
Publicado: (2022)

Therapeutical and Pharmaceutical Notes on Cimicifuga
por: Parrish, Edward
Publicado: (1861)

The Influence of Cimicifuga Racemosa on Parturition
por: Knox, J. Suydam
Publicado: (1885)

Three New Cycloartenol Triterpenoid Saponins from the Roots of Cimicifuga simplex Wormsk
por: Kuang, Haixue, et al.
Publicado: (2011)

Dual Effects of Cell Free Supernatants from Lactobacillus acidophilus and Lactobacillus rhamnosus GG in Regulation of MMP-9 by Up-Regulating TIMP-1 and Down-Regulating CD147 in PMA- Differentiated THP-1 Cells
por: Maghsood, Faezeh, et al.
Publicado: (2018)

Antioxidant activity and mechanism of Rhizoma Cimicifugae
por: Li, Xican, et al.
Publicado: (2012)

Cimicifuga, in Its Relation to Acute Catarrh
por: Smith, C. Carleton
Publicado: (1882)

Heart Troubles & Cactus Grandiflora & Cimicifuga
Publicado: (1881)

Novel cycloartane triterpenoid from Cimicifuga foetida (Sheng ma) induces mitochondrial apoptosis via inhibiting Raf/MEK/ERK pathway and Akt phosphorylation in human breast carcinoma MCF-7 cells
por: Sun, Hai-yan, et al.
Publicado: (2016)

Propolis Exerts an Anti-Inflammatory Effect on PMA-Differentiated THP-1 Cells via Inhibition of Purine Nucleoside Phosphorylase
por: Alqarni, Abdulmalik M., et al.
Publicado: (2019)

The insight of in vitro and in silico studies on cholinesterase inhibitors from the roots of Cimicifuga dahurica (Turcz.) Maxim.
por: Kim, Jang Hoon, et al.
Publicado: (2018)

Apoptosis-independent cleavage of RhoGDIβ at Asp19 during PMA-stimulated differentiation of THP-1 cells to macrophages
por: Ota, Takahide, et al.
Publicado: (2017)

Hepatoprotective Triterpene Saponins from the Roots of Glycyrrhiza inflata
por: Zheng, Yun-Feng, et al.
Publicado: (2015)

Nucleophosmin Mutants Promote Adhesion, Migration and Invasion of Human Leukemia THP-1 Cells through MMPs Up-regulation via Ras/ERK MAPK Signaling
por: Xian, Jingrong, et al.
Publicado: (2016)

Matrix Metalloproteinases (MMPs) and Inhibitors of MMPs in the Avian Reproductive System: An Overview
por: Hrabia, Anna
Publicado: (2021)

The complete chloroplast genome of the medicinal plant Paederia foetida L.
por: Wang, Wei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_v4cqi7ipevdecqkh6smcm7ks1r