Directed evolution of mevalonate kinase in Escherichia coli by random mutagenesis for improved lycopene

Lycopene is a terpenoid pigment that has diverse applications in the fields of food and medicine. Metabolic engineering in microbial hosts has shown that mevalonate kinase (MK, EC2.7.1.366) is one of the rate-limiting enzymes in the lycopene synthetic pathway. In this study, a directed evolution str...

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Detalles Bibliográficos
Autores principales: Chen, Hailin, Liu, Changqing, Li, Meijie, Zhang, Haibo, Xian, Mo, Liu, Huizhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080002/
https://www.ncbi.nlm.nih.gov/pubmed/35541305
http://dx.doi.org/10.1039/c8ra01783b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080002/
https://www.ncbi.nlm.nih.gov/pubmed/35541305
http://dx.doi.org/10.1039/c8ra01783b

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