Cargando…

One-pot sequential multicomponent reaction between in situ generated aldimines and succinaldehyde: facile synthesis of substituted pyrrole-3-carbaldehydes and applications towards medicinally important fused heterocycles

An efficient sequential multi-component method for the synthesis of N-arylpyrrole-3-carbaldehydes has been developed. This reaction involved a proline-catalyzed direct Mannich reaction-cyclization sequence between succinaldehyde and in situ generated Ar/HetAr/indolyl-imines, followed by IBX-mediated...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Anoop, Mir, Nisar A., Choudhary, Sachin, Singh, Deepika, Sharma, Preetika, Kant, Rajni, Kumar, Indresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080005/
https://www.ncbi.nlm.nih.gov/pubmed/35539447
http://dx.doi.org/10.1039/c8ra01637b