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Hypoglycemic effect and mechanism of isoquercitrin as an inhibitor of dipeptidyl peptidase-4 in type 2 diabetic mice

Glucagon-like peptide (GLP)-1 is a potent glucose-dependent insulinotropic gut hormone released from intestinal L cells. The aim of this study was to investigate isoquercitrin as an inhibitor of dipeptidyl peptidase IV (DPP-IV) and determine whether it affects GLP-1 release in normal mice and NCI-H7...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Zhang, Shi-Tao, Yin, Yan-Chun, Xing, Shu, Li, Wan-Nan, Fu, Xue-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9080018/
https://www.ncbi.nlm.nih.gov/pubmed/35541310
http://dx.doi.org/10.1039/c8ra00675j